Twenty-nine Wilms' tumors of 144 reseated renal neoplasms during the Period 1968
to 1982 are reviewed. Twenty-six cases are analyzed clinically and 25 cases are
reexamined microscopically. Classification of the tumor an4 clinical staging are based on
the National Wilms' Tumor Study. The clinical groups Ⅰ, Ⅱ, Ⅲ were 13, 6, 7 cases,
respectively. The epithelial predominant, mixed, blastemal predominent and stromal
predominent tripes were 3, 8, 5 and 9 cases, respectively. Eleven cases showed diffuse
anaplasia. Four of them were stromal, diffuse anaplasia and the types of malignancy
were rhabdomyosarcoma(3 cases) and clear cell sarcoma(1 case). Gross findings of the
tumors were greatly variable, however, those matched well to the microscopic findings.
So classification based on gross as well as microscopic findings was thought to be
superior to that based on simple collection of microscopic slides.
Five cases showing no evidence of recurrence or metastasis during the period of
follow-up more than one year and two cases with metastasis but survival over 2 years
are classified into good prognostic group. Four of them were stromal, no anaplasia type
and clinical group 1. Six cases showing widespread metastasis or rapid recurrence of
tumor resulting in death or giving up the treatment were classified into poor prognostic
group. Factors related to their poor prognosis were older age, high clinical stage and
histologic features of anaplasia. All the cases with poor prognosis showed evidences of
recurrence or metastasis within one year. The reseated kidneys of the cases with good
prognosis was heavier thats those of the cases with poor prognosis.
Six cases showed significant rhabdoid differentiation. Three cases were associated
with renal dysplasia. Two cases were adult Wilms' tumors.
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